目前，部分民族药用植物正面临着资源日渐匮乏、尚未得到合理利用和质量控制难度大等问题，且许多民族药用植物的作用机制有待深入研究。代谢组学可精确而全面地测定内源代谢物的组成和含量变化，在民族药用植物研究中应用广泛。本文对国内外多个数据库中2011年至2021年发表的相关论文进行了分析，并分析了代谢组学在民族药用植物研究中的应用以及民族药用植物代谢组学的未来研究方向。统计结果表明：近年来发表的民族药用植物代谢组学论文数量总体上逐年上升，主要涵盖传统知识评价、药效评价、物种鉴别和作用机制4个重点研究方向，其中，关于药效评价的论文最多（占比39.5%），关于作用机制的论文次之（占比35.5%）。代谢组学在民族药用植物的民间医学验证中应用广泛，有利于对民族药用植物传统知识的保护、推广和发展；利用代谢组学方法可探明民族药用植物的最佳采收时期和产地，指导其优质栽培，明确其药用部位，准确评估其有效性和安全性；利用代谢组学方法还能有效鉴别形态相似的民族药用植物，明确其作用机制，缩短新药开发周期。综上所述，代谢组学是明确民族药用植物药效、药理和毒理机制及物种鉴别的有效工具之一。将代谢组学与基因组学和蛋白质组学充分结合，能够更全面地了解民族药用植物次生代谢物的变化规律，有助于民族药用植物的深入研究和合理高效的开发利用，并可促进对民族药用植物资源及相关传统知识的保护。

 At present， some ethnomedicinal plants are facing the problems such as resource scarcity， insufficient rational utilization， and difficult quality control， and the mechanism of action of many ethnomedicinal plants need to be further researched. Metabolomics can accurately and fully assay the composition and content variation of endogenous metabolites， and are widely used in research of ethnomedicinal plants. The papers published during 2011-2021 in multiple domestic and foreign databases were analyzed in this paper， and the application of metabolomics in researches of ethnomedicinal plants and the further research directions of metabolomics of ethnomedicinal plants were analyzed. The statistic result shows that numbers of papers regarding metabolomics of ethnomedicinal plants increase year by year in general in recent years， which mainly cover four key research directions namely traditional knowledge evaluation， efficacy evaluation， species identification， and action mechanism， in which， papers regarding efficacy evaluation are the most （accounting for 39.5%）, followed by those regarding action mechanism （accounting for 35.5%）. Metabolomics are widely used in folk medical validation of ethnomedicinal plants， which is beneficial for preservation， popularization， and development of traditional knowledge of ethnomedicinal plants； using metabolomic methods can reveal the best harvest time and origin of ethnomedicinal plants， guide their high quality cultivation， clarify their medicinal parts， and accurately evaluate their effectiveness and safety； using metabolomic methods can also effectively identify the  ethnomedicinal plants with similar morphology， figure out their action mechanism， and shorten the development period of new drugs. Taken together， metabolomics is one of effective tools for clarifying the mechanisms of efficacy， pharmacology and toxicology and species identification of ethnomedicinal plants. When fully combine metabolomics with genomics and proteomics， the variation law of secondary metabolites in ethnomedicinal plants can be more comprehensively understood， which can contribute to deep investigation and rational and efficiency utilization of ethnomedicinal plants， and promote the preservation of ethnomedicinal plant resources and related traditional knowledge.