以样品中的薄荷脑含量为指标,通过单因素和正交实验对影响薄荷(Mentha haplocalyx Briq.)油超临界CO₂萃取的因素进行研究,筛选出薄荷油超临界CO2萃取的最佳条件。研究结果表明,影响样品中薄荷脑萃取率的因素从大到小依次为萃取压力、萃取温度、萃取时间、CO2流量。样品中薄荷脑含量最高的超临界CO2萃取条件为萃取压力10 MPa、萃取温度50℃CO₂流量30L·h^{- 1}且萃取时间1.5h。

According to content of menthol in sample, conditions for supercritical CO₂ extraction of essential oil from Mentha haplocalyx Briq. were studied through single factor and orthogonal experiment. The results showed that factors of effect on content of menthol in sample in order from large to small were extraction pressure, temperature, time and CO₂ flow rate. The optimized extraction conditions were pressure 10 MPa, temperature 50℃, CO₂ flow rate 30L·h^{- 1}and extraction time 1.5h.