2024年4月29日 星期一
月腺大戟根中有效成分乙素和丙素的结构研究
Studies on the active compound B and C in the root of Euphorbia ebracteolata Hayata
1992年 第1卷 第3期 页码[6-9] 下载全文[0.5MB]
| 摘要 | 本文主要报道从月腺大戟(Euphorbia ebracteolata Hayata)根中分离出的对结核菌有抑制作用的晶Ⅵ(乙素)和晶Ⅶ(丙素)的化学结构。经化学反应及光谱鉴定,确定晶Ⅵ为2,4-二羟基-6-甲氧基-3-甲基-苯乙酮,晶Ⅶ为2-羟基-6-甲氧基-3-甲基-1-苯乙酮-4-6-葡萄糖甙。乙素为首次分离的天然产物,丙素为新的化合物。该植物提取物对结核病有明显疗效。 |
| Abstract | Two compounds were obtained from acidic alcoholic extract in the root of Euphorbia ebracteolata Hayata. By spectral evidence and chemical reactions, 2, 4- dihydroxy- 6-methoxy-3-methyl-acetophenone (B) was identified as a new natural product for the first time and the other, a new compound, named 2- hydroxy- 6- methoxy- 3- methyl-acetophenone-4-β-glucoside (C). The two compounds (B, C ) showed inhibitory effect against tuberculosis bacillus. |
| 关键词 | 月腺大戟; 2,4-二羟基-6-甲氧基-3-甲基-苯乙酮; 2-羟基-6-甲氧基-3-甲基-1-苯乙酮-4-β-葡萄糖甙 |
| Key words | Euphorbia ebracteolata Hayata; 2, 4- dihydroxy- 6- methoxy- 3- methyl-acetophenone (B); 2-hydroxy-6-methoxy- 3-methyl-acetophenone- 4-β-glucoside (C). |
| 作者 | 张涵 庆 ，丁云梅 |
| 所在单位 | 江苏省植物研究所 , 南京 2 1 0 0 1 4 |
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