2021年10月17日 星期日
阴地蕨粗多糖对细菌和肿瘤细胞增殖的抑制作用
Inhibition effects of crude polysaccharides from Botrychium ternatum on bacteria and proliferation of tumor cells
2020年 第29卷 第4期 页码[69-71]    下载全文[0.7MB]  
Abstract

Crude polysaccharides were extracted from the whole plant of Botrychium ternatum (Thunb.) Sw. by using water extraction and ethanol precipitation method, and their inhibition effects on bacteria and proliferation of tumor cells were analyzed. The results show that the yield of crude polysaccharides from the whole plant of B. ternatum is 7.05%, and polysaccharides content in crude polysaccharides is 20.60%. Crude polysaccharides from B. ternatum show a certain inhibition effect on Escherichia coli and Staphyloccocus aureus, and that on E. coli is stronger than that on S. aureus, and the minimum inhibitory concentration is 0.206 and 0.309 mg·mL-1, respectively; crude polysaccharides from B. ternatum also show an inhibition effect on proliferation of A-549 and Hela cells, and that on proliferation of Hela cell is stronger than that on A-549 cell, the semi-inhibitory concentration is 138.90 and 109.23 μg·mL-1, respectively. Inhibition effects of crude polysaccharides from B. ternatum on bacteria and proliferation of tumor cells are all evidently smaller than those of several positive control, but show a tendency to gradually increase with the increase of mass concentration, and a certain concentration dependence.

关键词阴地蕨; 粗多糖; 抑菌作用; 肿瘤细胞增殖
Key wordsBotrychium ternatum (Thunb.) Sw.; crude polysaccharides; bacteriostasis; proliferation of tumor cells
作者周施雨1a,2, 钱志萍1b, 曹东东1a, 於俊杰1a, 游蕤翔1a, 戴锡玲1a
所在单位1. 上海师范大学: a. 生命科学学院, b. 环境与地理科学学院, 上海 200234; 2. 上海市第一人民医院, 上海 200080
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基金项目上海市绿化和市容管理局科学技术攻关项目(G152430); 上海植物种质资源工程技术研究中心项目(17DZ2252700)