2024年3月29日 星期五
甘薯和薯蓣块茎水提物对糖尿病小鼠的降血糖作用
Hypoglycemic effects of tuber aqueous extracts of Dioscorea esculenta and D. polystachya on diabetic mice
2021年 第30卷 第6期 页码[70-72]    下载全文[2.9MB]  
Abstract

To clarify the hypoglycemic effects of tuber aqueous extracts of Dioscorea esculenta (Lour.) Burkill and D. polystachya Turcz., effects of 10 and 20 g·kg-1·d-1 tuber aqueous extracts of D. esculenta ‘Tianyu No. 1’ and D. polystachya ‘Tiegun’ on body mass and blood glucose level of diabetic mice were assayed by taking 0.2 g·kg-1·d-1 metformin hydrochloride and 0.6 g·kg-1·d-1 Xiaoke pills as positive controls. The results show that after 3 weeks of intragastric administration with different doses of tuber aqueous extracts of ‘Tianyu No. 1’ and ‘Tiegun’, the average body mass of diabetic mice significantly increases, while the average blood glucose level significantly decreases; in which, compared with the diabetic model group, 20 g·kg-1·d-1 tuber aqueous extracts of ‘Tianyu No. 1’ and ‘Tiegun’ can increase the average body mass of mice by 17.6% and 18.1% respectively and decrease the blood glucose level by 23.0% and 22.3% respectively, and the promotion effect on body mass and the hypoglycemic effect of diabetic mice are close to those of positive controls. It is suggested that as medicinal and edible plants, tuber aqueous extracts of ‘Tianyu No. 1’ and ‘Tiegun’ can exert auxiliary hypoglycemic effects.

关键词甘薯; 薯蓣; 水提物; 降血糖; 体质量
Key wordsDioscorea esculenta (Lour.) Burkill; D. polystachya Turcz.; aqueous extract; hypoglycemic effect; body mass
作者谢鹏飞, 简暾昱, 陈闽, 孙小芹, 刘佳
所在单位江苏省中国科学院植物研究所(南京中山植物园), 江苏 南京 210014
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基金项目江苏省自然科学基金青年基金项目(BK20200289; BK20180316); 省属公益类科研院所自主科研课题(BM2018021-2)