2024年2月25日 星期日
丹参四倍体优良品系有效成分的含量测定及药理学试验
Determination of effective constituents in autotetraploid elite line of Salvia miltiorrhiza Bunge and primary pharmacological experiments
2001年 第10卷 第2期 页码[7-10]    下载全文[0.7MB]  
摘要

运用HPLC法测定丹参 (Salvia miltiorrhiza Bunge)同源四倍体优良品系 6 1 2 2 2及安徽、江苏和陕西产丹参不同部位、不同生长年限的有效成分 (3种丹参酮和 2种水溶性酚酸 )含量。丹参品系 6 1 2 2 2的有效成分含量明显高于其他产地丹参的含量 ;根中有效成分含量明显高于茎和叶的含量 ;丹参酮和丹参素的含量呈明显相关。初步药理实验结果表明 ,在相同剂量下 ,优良品系 6 1 2 2 2具有更好的药理活性。

Abstract

Three kinds of tanshinone and two kinds of water-soluble phenolic-acid in different parts of plants and different growth years of autotetraploid elite line 61-2-22 and different localities of Salvia miltiorrhiza Bunge were determined by HPLC .The results indicated that the contents of effective constituents in the new autotetraploid of Salvia miltiorrhiza were significantly higher than that in other samples .The contents of effective constituents in roots were significantly higher than that in stems and leaves .The content of tanshinone was closely related to the content of danshensu in all tested materials .Primary pharmacological experiments indicated that the new autotetraploid line of Salvia miltiorrhiza showed more active pharmacological effects .
 

关键词丹参; 同源四倍体; 丹参酮类; 丹参素; HPLC;
Key wordsSalvia miltiorrhiza Bunge; autotetraploid; tanshinone; danshensu; HPLC
作者朱丹妮, 高山林, 卞云云, 程心玟
所在单位中国药科大学, 江苏 南京 210038
点击量970
下载次数687
基金项目国家科技部“ 九五” 国家级重点科技成果推广项 目(97100504A) 的一部分